Reflections on Positive Emotions and Upward Spirals
Reflections on Positive Emotions and Upward Spirals Barbara L. Fredrickson1 and Thomas Joiner2 Barbara L. Fredrickson 1University of North Carolina at Chapel Hill Find articles by Barbara L. Fredrickson Thomas Joiner 2Florida State University Find articles by Thomas Joiner Author information Copyright and License information Disclaimer 1University of North Carolina at Chapel Hill 2Florida State […]
Theories of Aging: An Ever-Evolving Field
Senescence has been the focus of research for many centuries. Despite significant progress in extending average human life expectancy, the process of aging remains largely elusive and, unfortunately, inevitable. In this review, we attempted to summarize the current theories of aging and the approaches to understanding it. Keywords: aging, life expectancy, reactive oxygen species, accumulation […]
Markers of cellular senescence. Telomere shortening as a marker of cellular senescence
Markers of cellular senescence. Telomere shortening as a marker of cellular senescence Alexandra Bernadotte,#1,2 Victor M. Mikhelson,#3 and Irina M. Spivak#3,4,5 Alexandra Bernadotte 1 Karolinska Institute, Department of Medical Biochemistry and Biophysics, Stockholm, 14157, Sweden 2 St. Petersburg Institute of Bioregulation and Gerontology, Russian Academy of Sciences, Saint-Petersburg, 197110 Russia Find articles by Alexandra Bernadotte […]
Dopamine reward prediction error coding
Abstract Reward prediction errors consist of the differences between received and predicted rewards. They are crucial for basic forms of learning about rewards and make us strive for more rewards—an evolutionary beneficial trait. Most dopamine neurons in the midbrain of humans, monkeys, and rodents signal a reward prediction error; they are activated by more reward […]
Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
Cell Signal. Author manuscript; available in PMC 2013 May 1. Published in final edited form as: Cell Signal. 2012 May; 24(5): 981–990. Published online 2012 Jan 20. doi: 10.1016/j.cellsig.2012.01.008 PMCID: PMC3454471 NIHMSID: NIHMS351530 PMID: 22286106 Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling Paul D. Ray, Bo-Wen Huang, and Yoshiaki Tsuji* Author information […]